AbbVie says blood cancer drug fails late-stage trial

- 6/16/2025

</head><body><p>(Reuters) -AbbVie said on Monday its treatment for a group of blood cancers failed to meet the main goal of significantly improving the overall survival of patients in a late-stage trial.</p><p>The company was testing the drug, Venclexta, in newly-diagnosed patients with higher-risk myelodysplastic syndromes (MDS), a group of cancers in which the bone marrow doesn't produce enough healthy blood cells.</p><p>According to the American Cancer Society, there are between 10,000 and 15,000 new cases of MDS each year in the country.</p><p>Venclexta is already approved for the treatment of another type of blood cancer called leukemia and is jointly developed by AbbVie and Swiss drugmaker Roche.</p><p>AbbVie said the new trial data does not impact any current approvals for the drug.</p><p>U.S.-based AbbVie reported global Venclexta sales of about $2.6 billion in 2024.</p><p>Venclexta works by blocking the action of the BCL-2 protein, which is responsible for prolonging the life of cancer cells.</p><p>The drug is also being tested for the treatment of other blood cancers such as non-Hodgkin lymphoma and multiple myeloma.</p><p> (Reporting by Christy Santhosh in Bengaluru; Editing by Leroy Leo)</p></body></html></p> <div id="news-wrapper"> <div class="thumbnail additional-resources client-content-image-box"> <div class="box-image" style="background-image: url(/images/home/news.jpg);"></div> <div class="caption"> <h3>Nationwide News</h3> <div> <p><a href='/veterans/news-article-detail.aspx?id=155542'>Grave of Black veteran of War of 1812 receives headstone</a></p> <p><a href='/veterans/news-article-detail.aspx?id=155541'>World War II veteran, motorcycle champion turns 102</a></p> <p><a href='/veterans/news-archive.aspx'>News Archive</a></p> </div> </div> </div> </div> </div> </div> </div> </section> </div>  <footer class="footer">  <div class="clearfix footerInfo"> <div class="container"> <div class="row"> <div class="col-sm-7 col-xs-12"> <div class="footerText"> <a href="http://www.trilogyir.com/" target="_blank" class="footerLogo"><img src="/images/Noc-Logo-white.png" alt="Footer Logo" style="width: 200px;"></a> <div class="genericContent" id="landingPageText"> <p>Network of Care for Service Members, Veterans & Their Families is an online information portal for individuals, families and social service agencies to serve those who have served our country. </p> </div> <h3 id="lblTechAssistance" style="color: #fff; 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AbbVie says blood cancer drug fails late-stage trial